ACNE pill Roaccutane could increase the risk of suicide, an inquest heard.

Tragic Angela Lee, 28, threw herself under a train after the drug allegedly triggered depression, a lawyer representing her family said.

Thousands of Brits use Roaccutane to combat their acne. The treatment has been linked to a series of UK suicides, although trials have declared it safe.

Unemployed Angela, from Ilford, East London, was prescribed Roaccutane last year and took the pills for three months.

Relatives yesterday told the inquest at Walthamstow that her acne improved but she felt "prematurely aged". Angela - who also suffered chronic fatigue syndrome - developed depression and killed herself last October.

Her family claim her depression deepened during and after the course of Roaccutane. Lawyer Ross Brain said: "There is clear evidence of some users of this drug experiencing acute depression and suicidal tendencies."

Angela's dermatologist Dr Sunil Chopra told the inquest it was unlikely the drug caused her suicide. Roaccutane maker Roche says acne itself can trigger depression by harming self-esteem.

After the hearing Mr Brain said: "In her suicide note Angela spoke about how Roaccutane had aged her body, how she would never get better, how there was no way out."

Michael Jackson : Acne problems during teenage years made MJ ‘paranoid’

Michael Jackson’s new tapes that have surfaced have revealed that the singer’s acne problems in his teenage years had an effect on him mentally and left him paranoid.

The King of Pop is heard saying in the tapes that he was extremely worried about his skin problem.

“You can clear up physically but still mentally you’re scarred – so you really haven’t improved,” the News of the World quoted him as saying in the tape.

“My skin broke out real bad. It was tough – especially after everyone had been calling me cute for such a long time. And the more I worried about it the worse I got,” he added.

Apparently, the late singer only felt comfortable with his looks on stage when it was primarily hidden with his hat.

He said: “I wore hats, I kept my head down all the time, I wouldn’t look at people when I talked to them.

“I wouldn’t say nothin’ hardly. It was terrible. I felt I didn’t have anything to be proud of. My success meant nothing.

“On stage I didn’t think about it, it was gone. But when I came off stage, there it was again.”

The ‘Thriller’ hitmaker defended his decision to undergo surgery to make his looks better.

However, he did not want people to know about his skin problems.

He said: “I’m a perfectionist when it comes to skin. I would look in the mirror and I didn’t like they way I looked, so.. of course, never print this. Please don’t…

“But take Marilyn Monroe, and all those people. They got the works. Julie Andrews, Raquel Welch. Even Elvis. You look at his nose and the difference.. it’s true. But nobody ever mentions it.”

Jackson denied that by having his skin bleached white he was escaping the black community.